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Stochastic approach to the process of red cell destruction

100%

Kimmel M., Ważewska-Czyżewska M.

Applicationes Mathematicae

1980-1983

tom 17

nr 2

217-225

Mathematical problems of the dynamics of the red blood cells

100%

Ważewska-Czyżewska M., Lasota A.

Mathematica Applicanda

1976

tom 4

nr 6

The purpose of this paper is to construct a model for the process of generation and degeneration of red blood cells, taking into account biological-medical experimental data. The paper contains four sections. The first section presents basic biological facts enabling the reader who is not a specialist to understand this process. Section 2 is devoted to constructing an analytic model which uses a first order linear partial differential equation and a nonlinear integral equation. Section 3 lists some of the simplest mathematical properties of this model and the biological consequences arising from it. Section 4 gives a simplified model which can be described in terms of a nonlinear ordinary differential equation with a delayed parameter. The properties of this simple equation are of interest from both a mathematical and a biological point of view. In particular, the proof of the existence of periodic equations requires the application of a nontrivial version of a theorem on fixed points. The problem of the stability of this periodic solution is open. The problem is important in that the existence of a stable periodic solution gives a theoretical explanation of certain types of blood diseases.

Ograniczanie wyników

1 Applicationes Mathematicae

1 Mathematica Applicanda

2 Ważewska-Czyżewska M.

1 Kimmel M.

1 Lasota A.

1 1982

1 1976

Wyniki wyszukiwania

Stochastic approach to the process of red cell destruction

Mathematical problems of the dynamics of the red blood cells