Sensitivity Analysis Aimed at Finding Potential Molecular Drug Targets

• Autorzy: Jaroslaw Smieja , Małgorzata Kardyńska , Marta Pudlo
• Języki publikacji: EN

Abstrakty

EN

Sensitivity analysis has become one of the standard tools in analysis of models of intracellular processes. Various methods have been proposed, developed for either local or global sensitivity of systems under investigation. In this work, we propose a method that may be used to find potential molecular drug targets, taking into account heterogeneity of population of cells with respect to their responses to a particular drug agent.

Słowa kluczowe

EN

sensitivity analysis, signaling pathways, molecular drug targets

• Wydawca: Polish Mathematical Society
• Czasopismo: Mathematica Applicanda
• Rocznik: 2019
• Tom: 47
• Numer: 2

Daty

wydano

2019

online

2019-08-20

Twórcy

autor

Jaroslaw Smieja

autor

Małgorzata Kardyńska

autor

Marta Pudlo

Identyfikatory

DOI

10.14708/ma.v47i2.6488