We study Palamodov's derived projective limit functor Proj¹ for projective spectra consisting of webbed locally convex spaces introduced by Wilde. This class contains almost all locally convex spaces appearing in analysis. We provide a natural characterization for the vanishing of Proj¹ which generalizes and unifies results of Palamodov and Retakh for spectra of Fréchet and (LB)-spaces. We thus obtain a general tool for solving surjectivity problems in analysis.