Immunotherapy with interleukin-2: A study based on mathematical modeling

• Autorzy: Sandip Banerjee
• Języki publikacji: EN

Abstrakty

EN

The role of interleukin-2 (IL-2) in tumor dynamics is illustrated through mathematical modeling, using delay differential equations with a discrete time delay (a modified version of the Kirshner-Panetta model). Theoretical analysis gives an expression for the discrete time delay and the length of the time delay to preserve stability. Numerical analysis shows that interleukin-2 alone can cause the tumor cell population to regress.

Słowa kluczowe

EN

effector cells; tumor cells; interleukin-2; discrete time delay

• Wydawca: University of Zielona Gora Press
• Czasopismo: International Journal of Applied Mathematics and Computer Science
• Rocznik: 2008
• Tom: 18
• Numer: 3
• Strony: 389-398

Daty

wydano

2008

otrzymano

2007-08-03

poprawiono

2008-02-22

Twórcy

autor

Sandip Banerjee

• Indian Institute of Technology and Science Rooorkee (IITR), Roorkee 247667, Uttarakhand, India

Bibliografia

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Identyfikatory

DOI

10.2478/v10006-008-0035-6