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Quality improvement of rule-based gene group descriptions using information about GO terms importance occurring in premises of determined rules

100%
Sikora M., Gruca A.
International Journal of Applied Mathematics and Computer Science
|
2010
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tom 20
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nr 3
555-570
EN
In this paper we present a method for evaluating the importance of GO terms which compose multi-attribute rules. The rules are generated for the purpose of biological interpretation of gene groups. Each multi-attribute rule is a combination of GO terms and, based on relationships among them, one can obtain a functional description of gene groups. We present a method which allows evaluating the influence of a given GO term on the quality of a rule and the quality of a whole set of rules. For each GO term, we compute how big its influence on the quality of generated set of rules and therefore the quality of the obtained description is. Based on the computed quality of GO terms, we propose a new algorithm of rule induction in order to obtain a more synthetic and more accurate description of gene groups than the description obtained by initially determined rules. The obtained GO terms ranking and newly obtained rules provide additional information about the biological function of genes that compose the analyzed group of genes.
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Improving prediction models applied in systems monitoring natural hazards and machinery

100%
Sikora M., Sikora B.
International Journal of Applied Mathematics and Computer Science
|
2012
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tom 22
|
nr 2
477-491
EN
A method of combining three analytic techniques including regression rule induction, the k-nearest neighbors method and time series forecasting by means of the ARIMA methodology is presented. A decrease in the forecasting error while solving problems that concern natural hazards and machinery monitoring in coal mines was the main objective of the combined application of these techniques. The M5 algorithm was applied as a basic method of developing prediction models. In spite of an intensive development of regression rule induction algorithms and fuzzy-neural systems, the M5 algorithm is still characterized by the generalization ability and unbeatable time of data model creation competitive with other systems. In the paper, two solutions designed to decrease the mean square error of the obtained rules are presented. One consists in introducing into a set of conditional variables the so-called meta-variable (an analogy to constructive induction) whose values are determined by an autoregressive or the ARIMA model. The other shows that limitation of a data set on which the M5 algorithm operates by the k-nearest neighbor method can also lead to error decreasing. Moreover, three application examples of the presented solutions for data collected by systems of natural hazards and machinery monitoring in coal mines are described. In Appendix, results of several benchmark data sets analyses are given as a supplement of the presented results.
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