Computational determination of the optimal dose of the cis-platinum to maximize the life time of patients diagnosed with cancer.

• Autorzy: Emilia Kozłowska , Krzysztof Puszynski
• Języki publikacji: EN

Abstrakty

EN

In this work, we present the results of our study over the expected lifetime of the patients diagnosed with relapsed squamous cell lung cancer, which is a subtype of non-small cell lung cancer, treated by cis-platinum. We developed the mathematical model consist of cells sensitive and resistant to cis-platinum. The performed simulations suggest that the best strategy to prolong the patient lifetime after diagnosis is to keep the sensitive cells subpopulation at the constant level instead of killing all of them.

Słowa kluczowe

EN

therapy optimization, cis-platinum, cancer grow, resistance to the drug

• Wydawca: Polish Mathematical Society
• Czasopismo: Mathematica Applicanda
• Rocznik: 2019
• Tom: 47
• Numer: 2

Daty

wydano

2019

online

2019-08-22

Twórcy

autor

Emilia Kozłowska

autor

Krzysztof Puszynski

Identyfikatory

DOI

10.14708/ma.v47i2.6485