A four phase model air/glass/indium doped tin oxide/TiO2 has been studied by modifying Rouard’s model to calculate the final transmittance from TiO2 layer to be used as photoanode in dye-sensitized solar cells. An optical simulation for the reflectance and transmittance has been executed for the constructed nanocrystalline TiO2 films. To validate the theoretical results TiO2 film has been deposited onto indium doped tin oxide (ITO) layer by sol-gel dip coating technique. It has been found that the incident light suffers losses by 5-15% on passage through TiO2 coated ITO layer. Experimentally it has been observed on the basis of efficiency value that meso-nano combination is the best candidate to be used as photoanode in a dye-sensitize solar cell.