The optimal experiment for estimating the parameters of a nonlinear regression model usually depends on the value of these parameters, hence the problem of designing experiments that are robust with respect to parameter uncertainty. Sequential designpermits to adapt the experiment to the value of the parameters, and can thus be considered as a robust design procedure. By designing theexperiments sequentially, one introduces a feedback of information, and thus dynamics, into the design procedure. Several sequential schemes, corresponding to different control policies, are considered. The optimal one corresponds to closed-loop control, and is solution of a stochastic dynamic-programming problem, which is extremely difficult to solve. A suboptimal strategy is proposed, which relies ona normal approximation of the future posterior of θ, independent of future observations. The design criterion obtained involves several mathematical expectations, which are approximated by Laplace method. Finally, stochastic approximation algorithms are also suggested to determine (sub)optimal sequential experiments without having to compute expectations.