EN
Let t be a regular operator between Hilbert C*-modules and $t^{†}$ be its Moore-Penrose inverse. We investigate the Moore-Penrose invertibility of the Gram operator t*t. More precisely, we study some conditions ensuring that $t^{†} = (t*t)^{†}t* = t*(tt*)^{†}$ and $(t*t)^{†} = t^{†}t*^{†}$. As an application, we get some results for densely defined closed operators on Hilbert C*-modules over C*-algebras of compact operators.