Thermodynamics of DNA microarrays

• Autorzy: Enrico Carlon
• Języki publikacji: EN

Abstrakty

EN

DNA microarrays have been widely used in molecular biology laboratories. The main current application of these devices is the determination of the gene expression level for thousands of genes simultaneously. Here we review a recently introduced physical model for hybridization (i.e. the binding of complementary DNA strands) in Affymetrix arrays and compare it to experimental results. The experimental data follow rather well the microscopic model and the approach offers several advantages compared to traditional methods of microarray data analysis.

Kategorie tematyczne

• 80A10: Classical thermodynamics, including relativistic
• 92E20: Classical flows, reactions, etc.

• Wydawca: Institute of Mathematics Polish Academy of Sciences
• Czasopismo: Banach Center Publications
• Rocznik: 2008
• Tom: 80
• Numer: 1
• Strony: 229-233

Daty

wydano

2008

Twórcy

autor

Enrico Carlon

• Interdisciplinary Research Institute of Lille, École Polytechnique Universitaire de Lille (Polytech'Lille), Cité Scientifique, F-59652 Villeneuve d'Ascq, France

Identyfikatory

DOI

10.4064/bc80-0-13